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Methamphetamine is a stimulant that the source describes in powder, pill, and crystal forms, with several routes of use. The overview discusses dopamine effects, short- and long-term health consequences, and research on changes in cognition, memory, and brain function associated with prolonged use.
Cocaine is described as an addictive stimulant that may be snorted, rubbed on the gums, injected, or smoked as crack. The overview covers its effects on the brain and body, risks associated with repeated use or adulterated supply, and treatment approaches discussed in the source.
MDMA, also called Ecstasy or Molly, is described as a synthetic drug that affects mood, perception, energy, and sensory experience. The source outlines common forms of use, changes to dopamine, norepinephrine, and serotonin activity, and reported short- and longer-term health effects.
The article reviews evidence that high-dose amphetamine or methamphetamine can produce a paranoid psychosis, sometimes with hallucinations, in a clear state of consciousness. Historical case reports and experimental studies describe varied courses after drug cessation, including rapid remission and, in some cases, prolonged vulnerability or recurrence.
The article surveys research and case reports linking cannabis use, including synthetic cannabinoids, with psychotic experiences and other psychiatric symptoms. It summarizes longitudinal evidence associating regular or heavy cannabis use with increased psychosis risk, while emphasizing that observational findings leave uncertainty about causation and individual vulnerability.
